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Collaboration › Details

Shimadzu–CovalX: MegaTOF MALDI mass spectrometer, –201005 collab developm by integrating AXIMA MALDI system with HM2 high-mass system

 

	Period	2010-05-23
	Partner, 1st	Shimadzu Corporation
	Group	Shimadzu (Group)
	Partner, 2nd	CovalX AG
	Group	CovalX (Group)
	Product	AXIMA MegaTOF™ MALDI Mass Spectrometer
	Product 2	AXIMA™ mass spectrometer (product series)

CovalX AG. (5/20/10). "Press Release: MegaTOF MALDI Mass Spectrometer. A New MALDI Instrument by Shimadzu and CovalX".

Shimadzu and CovalX have partnered to offer an integrated MALDI solution for ultrahigh mass applications. The MegaTOFTM has been developed by optimizing the integration of a high performance Shimadzu linear MALDI TOF mass spectrometer with CovalX high-mass system, allowing outstanding detection of macromolecules up to 1500 kDa. MegaTOFTM MALDI MS gives access to a broad range of applications, including direct analysis of protein-protein interactions such as complexes or biopharmaceutical aggregates. For these analyses, CovalX developed special cross-linking reagents and buffers for a fast and specific stabilization of protein interactions. The reagents contain 'cocktails' of cross-linkers with different spacer lengths able to covalently bind specific protein complexes with a high degree of efficiency. The specificity facilitates the stabilization of covalent protein complexes - even in contaminated or unpurified samples. The High-Mass MALDI applications are also available for the existing Shimadzu AXIMA MALDI (Assurance, Confidence, Performance) by retrofitting CovalX's HM2 or HM2 TUVO high-mass system on these instruments.
MegaTOFTM MALDI Mass Spectrometer will be launched at the 58th ASMS conference in Salt Lake City, May 23-27th. The instrument will be exhibited during the conference at Shimadzu Hospitality Suite (253 A&B). For more information, you can meet our teams at the conferences (CovalX Booth 75; Shimadzu Booth 86).

Record changed: 2011-11-25

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• [4] Shimadzu Corporation. (5/10/12). "Press Release: Operating Results and Financial Position For the Fiscal Year Ended March 31, 2012". Kyoto....
• [5] [iito] Business Intelligence. (4/20/12). "[MSC] Newsletter March 2012". Bremen....
• [6] Shimadzu Scientific Instruments, Inc.. (4/9/12). "Press Release: Shimadzu Scientific Instruments and the University at Texas at Arlington Form Shimadzu Center for Advanced Analytical Chemistry"....
• [7] University of Texas at Arlington. (4/6/12). "Press Release: Shimadzu Gift Brings Millions in Scientific Equipment to UT Arlington"....
• [8] Shimadzu Corporation. (4/4/12). "Press Release: »Excellence in Science« Established as Brand Statement for Shimadzu Group"....
• [9] Sony DADC. (3/21/12). "Press Release: Shimadzu/Kratos and Sony DADC Sign New Agreement to Extend Collaboration". Manchester....
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