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Biognosys AG. (2/19/13). "Press Release: Plasma Glycoproteome Analysis in Clinical Biomarker Research".

Organisations Organisation Biognosys AG
  Organisation 2 Institute for Systems Biology (ISB) (Seattle)
Product Product  multiple reaction monitoring (MRM) technology
     


Together with the group of scientist from the ETH Zurich and ISB Seattle, Biognosys contributed to a pioneering paper on high-throughput plasma glycoproteome analysis.

The paper describing biomarker validation workflow in plasma sub-proteome is just published in Molecular & Cell Proteomics.

We demonstrated that 48 N-glycoproteins spanning five orders of magnitude in abundance can be reproducibly quantified with multiplexed scheduled MRM approach. Furthermore, a set of clinically-relevant markers was quantified across 120 samples from patients with three different malignancies enabling statistical testing with high sensitivity.

   
Record changed: 2016-03-19

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