Advertisement

Picture EBD Group BIO-Europe Spring 2017 BES Barcelona Spain March 600x60px
Document › Details

Metabolon, Inc.. (8/3/09). "Press Release: New Research Offers Insight into Metabolomics Methods. Publication Details Technology for the Simultaneous Quantification and Qualification of Metabolites". Research Triangle Park, NC.

Organisation Organisation Metabolon Inc.
  Group Metabolon (Group)
Products Product LC/MS (liquid chromatography/mass spectrometry)_other
  Product 2 GC/MS system
     


Metabolon, Inc., the leader in metabolomics-driven biomarker discovery and analysis, today announced the publication of a paper describing Metabolon's biochemical profiling technology. The paper, titled "Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems", appears in Analytical Chemistry.

"This paper describes a general method of profiling biochemicals in a high-throughput and scalable manner which enables the simultaneous quantification and identification of metabolites," explained Anne M. Evans, Ph.D., senior research scientist with Metabolon and lead author of the publication.

The system described in the paper is an integral part of Metabolon's commercial metabolomics platform. In addition to the UHPLC-MS/MS system, Metabolon employs a GC-MS system to provide additional breadth of coverage of biochemicals and metabolites.

Specific challenges associated with metabolomics analyses addressed in this paper include:

* Analytical platform variations and the specific advantages of a mass-spectrometry-based approach
* Discussion about the chemocentric approach to metabolite identification
* Challenges in identification and relative quantification of metabolites including elimination of experimental artifacts
* The large number of molecules able to be identified through this approach

Click here to read the complete abstract of the publication.

About Metabolon
Metabolon is a diagnostics and services company offering the industry's leading biochemical profiling platform. Metabolon's patented platform provides a global analysis of complex biological samples for the discovery of markers and pathways associated with drug action and disease. This metabolomics-driven approach enables the identification of biomarkers useful for the development of a wide range of diagnostics and provides insight into complex biochemical processes such as drug action, toxicology and bioprocess optimization. For more information about Metabolon, please visit www.metabolon.com.

   
Record changed: 2016-03-19

Advertisement

Picture EBD Group BIO-Europe Spring 2017 BES Barcelona Spain March 600x60px

More documents for Metabolon (Group)


To subscribe to our free, monthly mass spectrometry newsletter, please send an e-mail to info@iito.de and simply fill the subject line with the word »MSC newsletter«

To get even more information, please take a look at our [gs] professional services offering and read the gene-sensor Product Flyer [PDF file]

Please visit also our web portals for the Eurpean life sciences and the life sciences in German-speaking Europe (DE, AT & CH) at Life-Sciences-Germany.com and Life-Sciences-Europe.com

Advertisement

Picture AB Sciex Berliner LCMSMS Symposium 2017 Middle 600x60px




» top

Advertisements

Picture [iito] Twitter iitoLifeScience Life Sciences Mass Spec 120x120px BCNP Consultants European Chemistry Partnering 2017 Ffm Germany 120x180px Picture EBD Group BIO-Europe Spring 2017 BES Barcelona Spain March 120x180px Picture AB Sciex Berliner LCMSMS Symposium 2017 Right 120x80px Picture [LSE] Life-Sciences-Europe.com – The Business Web Portal 120x600px Banner Fairtec GmbH Solutions for Smarter Business Events Exhibitions 120x120px Picture [iito] Twitter iitoLifeScience Life Sciences Mass Spec 120x120px