Advertisement

Picture EBD Group BIO-Europe Spring 2017 BES Barcelona Spain March 600x60px
Document › Details

Protea Biosciences, Inc.. (9/8/10). "Press Release: Protea Biosciences Concludes New Technology License Agreement. LAESI Technology Identifies Viral-infected Cells in Minutes". Morgantown, WV.

Region Region ALL
Organisations Organisation Protea Biosciences Inc.
  Today Protea Biosciences Group Inc.
  Group Protea Biosciences (Group)
  Organisation 2 George Washington University, Dept. of Chemistry, Vertes Research Group
  Group George Washington University
Products Product LAESI technology (Laser Ablation Electrospray Ionization technology)
  Product 2 ionisation technology (mass spectrometry)
Index term Index term Protea Biosciences–George Washington Univ: LAESI technology, 201009– license ww excl from GWU research team of Prof Akos Vertes
Persons Person Turner, Stephen (Steve) (Protea Biosciences 201002 CEO)
  Person 2 Vertes, Akos (George Washington Univ 2000– Prof before Associate Prof since 1991)
     


Protea Biosciences, a leading developer of new bioanalytical technology, announced today that the company has concluded an exclusive, worldwide license agreement with George Washington University for commercial rights to a new technology that provides rapid identification of a broad range of chemicals and biomolecules. In an article published yesterday in the prominent journal PLoS ONE (http://dx.plos.org/10.1371/journal.pone.0012590), a team of researchers at George Washington University led by Akos Vertes, PhD., used the newly-developed LAESI technology to rapidly identify virally-infected human cells.

Known as Laser Ablation Electrospray Ionization or "LAESI" mass spectrometry, the technology is capable of directly identifying proteins, peptides, lipids, and metabolites found in biological samples, including tissue, blood, urine and even single cells. Extremely rapid (each analysis takes less than 2 seconds), sensitive and quantitative, LAESI also provides 3 dimensional mapping of biomolecules through depth profiling and lateral imaging. Proteins and metabolites can be identified and localized in cell structures, tissues and fluids. Little or no sample preparation is required.

"We believe LAESI technology holds the promise to meet the great need of biologists and medical professionals to directly identify biomolecules in biomedical samples, without the currently-required destructive and time-consuming sample preparation methods," stated Steve Turner, Protea CEO. He added, "We foresee a broad range of commercial applications in chemical and biological research, surgical pathology, clinical diagnostics, chemical and biological defense, forensics, agriculture, and many other fields. LAESI is a breakthrough technology of the first order".

LAESI technology was invented and developed in the laboratory of Dr. Akos Vertes Ph.D., Professor of Chemistry, Professor of Biochemistry & Molecular Biology, and Founder and Co-Director of the W.M. Keck Institute for Proteomics Technology, at the Department of Chemistry, George Washington University. LAESI has already been demonstrated to be a powerful research tool and many of ist applications have been published in peer-reviewed journals.

Professor Vertes commented, "LAESI represents a minimally invasive and minimally destructive approach to chemical analysis, which means that dynamic, even living cells or tissues can be probed for their molecular composition not only in three dimensions, but also with time. Small sample consumption of the LAESI analysis means that much of the sample remains available for additional investigation."

In collaboration with the Vertes laboratory, Protea scientists are developing instrumentation and software that will bring the capabilities of the LAESI technology to research laboratories worldwide, with the availability of the first instruments in 2011.

In their article in PLoS ONE (http://dx.plos.org/10.1371/journal.pone.0012590) published yesterday, Prof. Vertes and coworkers demonstrate high throughput, in situ metabolite profiling of virally transformed and oncogene expressing cells. Their findings facilitate the identification of virus-induced changes in the biochemical processes of the host cells. These new insights on the affected metabolic pathways can be used to better understand the molecular mechanisms of virally induced cell changes, which in turn can result in new treatment strategies.

Protea Biosciences, Inc. (www.proteabio.com) develops new bioanalytical technologies that enable the direct analysis of proteins, metabolites, and other biomolecules, and applies their technology to the development of new pharmaceuticals, products and services.

For more Information:

Protea Biosciences, Inc.,
955 Hartman Run Road,
Morgantown, WV 26507
Phone: 304.292.2226
Fax: 304.292.7101
stephen.turner@proteabio.com
www.proteabio.com

The George Washington University,
Washington D.C.
Emily Cain,
Associate Director of Media Relations
202--994--3087
eecain@gwu.edu

Link to PLoS ONE article: http://dx.plos.org/10.1371/journal.pone.0012590
Video article in JoVE on LAESI imaging: http://www.jove.com/index/details.stp?id=2097
Video article in JoVE on single cell analysis: http://www.jove.com/index/details.stp?id=2144

   
Record changed: 2016-03-19

Advertisement

BCNP Consultants European Chemistry Partnering 2017 Ffm Germany 600x60px

More documents for Protea Biosciences (Group)


To subscribe to our free, monthly mass spectrometry newsletter, please send an e-mail to info@iito.de and simply fill the subject line with the word »MSC newsletter«

To get even more information, please take a look at our [gs] professional services offering and read the gene-sensor Product Flyer [PDF file]

Please visit also our web portals for the Eurpean life sciences and the life sciences in German-speaking Europe (DE, AT & CH) at Life-Sciences-Germany.com and Life-Sciences-Europe.com

Advertisement

Picture EBD Group BIO-Europe Spring 2017 BES Barcelona Spain March 600x60px




» top

Advertisements

Picture [iito] Twitter iitoLifeScience Life Sciences Mass Spec 120x120px BCNP Consultants European Chemistry Partnering 2017 Ffm Germany 120x180px Picture EBD Group BIO-Europe Spring 2017 BES Barcelona Spain March 120x180px Picture AB Sciex Berliner LCMSMS Symposium 2017 Right 120x80px Picture [LSE] Life-Sciences-Europe.com – The Business Web Portal 120x600px Banner Fairtec GmbH Solutions for Smarter Business Events Exhibitions 120x120px Picture [iito] Twitter iitoLifeScience Life Sciences Mass Spec 120x120px