CombiSource™

	Next higher product group	ionisation technology (mass spectrometry)_other
	Status	2002-06-03 sales start
	Organisation	Bruker Daltonics Inc.
	Group	Bruker Corporation (Group)

Bruker Daltonics, Inc.. (6/3/02). "Press Release: Bruker Daltonics Announces Innovative CombiSource for FTMS". Orlando, FL.

At the American Society for Mass Spectrometry conference, Bruker Daltonics Inc. (NASDAQ: BDAL) today introduced a novel CombiSource(TM), which for the first time conveniently combines electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI). The CombiSource is an integrated, computer-switchable ion source for the APEX(R) IV series of Fourier Transform Mass Spectrometers (FTMS).

Today's life science applications increasingly require easy-to-use high-performance and high-throughput mass spectrometry systems. In proteomics in particular, ESI and MALDI are regarded as the key complementary ionization techniques of choice. To date, however, the switch between MALDI and ESI sources in FTMS has required either the exchange of source hardware, or even the swap of entire FTMS vacuum carts containing the different sources. To address this issue, Bruker Daltonics has developed the first fully-automated combined ESI and MALDI source for the APEX(R) IV series (patents pending).

This integrated approach to a dual ionization source allows automated unattended switching between ESI and MALDI in FTMS in less than 60 seconds. The CombiSource combines our MTP(TM) MALDI source, that has been developed originally for the FLEX(TM) series of MALDI-TOF mass spectrometers, with our high-performance Apollo(TM) ESI source. In the MALDI-mode of operation, analyte ions are desorbed from a 96- or 384-spot microtitre-plate AnchorChip(TM) target, and are then immediately thermalized to enhance FTMS sensitivity and resolution.

ABOUT BRUKER DALTONICS

Bruker Daltonics is a leading developer and provider of innovative life science tools based on mass spectrometry. For more information about Bruker Daltonics, please visit www.bdal.com

CAUTIONARY STATEMENT

Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. Any forward-looking statements contained herein are based on current expectations, but are subject to a number of risks and uncertainties. The factors that could cause actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating to technological approaches, product development, manufacturing, market acceptance, cost and pricing of Bruker Daltonics' products, dependence on collaborative partners, suppliers, FDA and other regulatory approvals to the extent applicable, competition, the intellectual property of others, patent protection and litigation and other risk factors discussed from time to time in Bruker Daltonics' reports or filings with the Securities and Exchange Commission. Bruker Daltonics expressly disclaims any obligation to update the information contained herein.

CONTACT:
Bruker Daltonics
Michael Willett,
(978) 663-3660, ext.1411
Michael.Willett@bdal.com

Record changed: 2011-11-25

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CombiSource™

Bruker Daltonics, Inc.. (6/3/02). "Press Release: Bruker Daltonics Announces Innovative CombiSource for FTMS". Orlando, FL.

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