Picture EBD Group Biotech Showcase 2024 San Francisco 650x100px
Collaboration › Details

Lonza–Agilent: analytical instruments, 202112– strategic alliance to integrate analytical technologies in Cocoon cell therapy production platform


Period Period 2021-12-15
Organisation Partner, 1st Agilent Technologies Inc. (NYSE: A)
Products Product analytical instrument
  Product 2 Cocoon® cell therapy manufacturing technology
Persons Person Ferrick, David (Agilent 201804 Senior Director Cell Analysis Division)
  Person 2 Ostrout, Nicholas (Lonza 202112 Senior Director Business Strategy + Implementation Personal Medicine)

Agilent Technologies Inc.. (12/15/21). "Press Release: Lonza and Agilent Announce Strategic Collaboration to Integrate New Analytical Technologies with Lonza’s Cocoon Platform". Basel & Santa Clara, CA.

> The collaboration aims to develop and integrate current and new analytical technologies into patient-scale cell therapy manufacturing workflows with the Cocoon® Platform.

> The companies aim to define the ideal Critical Quality Attributes (CQAs) required for cell therapies and build improved analysis packages to manufacture higher quality therapeutic products with greater consistency

> This collaboration brings both companies a step closer to their commitment to developing sustainable technologies and solutions that increase access to life-saving cell-based therapies.

Lonza, a leading global cell and gene therapy manufacturer, and Agilent Technologies, a leader in life sciences analytics, diagnostics, and applied chemical markets, today announced a collaboration that has the potential to transform the way personalized cell therapies are manufactured and realized.

Product quality and consistency are significant challenges for cell therapy manufacturing due to the complexity of the products and patient-specific variability. In addition, cell therapy products are largely defined by the process, which means minor changes during manufacturing could potentially cause major changes in the quality and efficacy. In-process controls and analytics are critically important in ensuring a consistent drug product, even in the presence of such variability, to provide real-time information on Critical Quality Attributes (CQA) throughout the manufacturing process and for quality control (QC) release testing.

By understanding the CQAs required for a potent and persistent cell therapy product, the manufacturing process can be “directed” in real-time. This is especially critical in autologous cell therapies due to the high variability of patient starting material.

This collaboration will integrate Agilent’s current and new analytics technologies and techniques into the Cocoon® Platform’s cell therapy manufacturing workflow to explore current and assess new CQAs required for the release of the therapeutic to the patient. By integrating Agilent analytical technologies both at-line and in-line within the Cocoon® Platform automated manufacturing workflows, manufacturers will be able to ensure that in-process controls and analytics can be employed on-demand to deliver a more consistent drug product.

Nicholas Ostrout, Senior Director, Business Strategy & Implementation, Personalized Medicine, Lonza, commented: “The integration of Agilent’s analytical technologies into the Cocoon® Platform’s manufacturing workflow has the potential to transform the way cell therapies are manufactured and released. The collaboration with Agilent is complementary to our long-term goals for the Cocoon® Platform and we are excited about this synergistic relationship. There is a huge opportunity through this partnership to determine what the ideal critical quality attributes are for manufacturing the most effective cell therapy, and drive the manufacturing, optimally in real-time, to meet those criteria.”

David Ferrick, Associate Vice President of New Market Development for Agilent’s Cell Analysis Division, added: “Merging Agilent’s unique cell analytics and engineering expertise with Lonza’s advanced biologics manufacturing capabilities will ensure the efficacious and sustainable development of autologous cell-based therapies. This timely combination is well-positioned to deliver the first fit-for-purpose solution for scaled manufacturing of autologous cell therapies.”

The Cocoon® Platform is an automated and closed platform for patient-scale cell therapy manufacturing, designed to overcome manufacturing challenges associated with patient-scale personalized medicines. The Cocoon® Platform is commercially available and gaining global traction as the go-to manufacturing platform for patient-scale cell therapies.

About Lonza

Lonza is the preferred global partner to the pharmaceutical, biotech and nutrition markets. We work to enable a healthier world by supporting our customers to deliver new and innovative medicines that help treat a wide range of diseases. We achieve this by combining technological insight with world-class manufacturing, scientific expertise and process excellence. Our unparalleled breadth of offerings enables our customers to commercialize their discoveries and innovations in the healthcare sector. Founded in 1897 in the Swiss Alps, today, Lonza operates across five continents. With approximately 15,000 full-time employees, we comprise high-performing teams and individual talent that make a meaningful difference to our own business, as well as to the communities in which we operate. The company generated sales of CHF 2.5 billion with a CORE EBITDA of CHF 847 million in H1 2021. Find out more at Follow @Lonza on LinkedIn. Follow @LonzaGroup on Twitter.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global leader in the life sciences, diagnostics, and applied chemical markets, delivering insight and innovation toward advancing the quality of life. Agilent’s full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers' most challenging questions. The company generated revenue of $6.32 billion in fiscal 2021 and employs 17,000 people worldwide. Information about Agilent is available at To receive the latest Agilent news, please subscribe to the Agilent Newsroom. Follow Agilent on LinkedIn, Twitter, and Facebook.

Media Contacts

Victoria Morgan
Lonza Group Ltd
+41 61 316 2283

Naomi Goumillout
Agilent Technologies, Inc
+1 978 314 1862

Record changed: 2022-01-02


Picture EBD Group World of Partnering Opportunities 650x200px

More documents for Lonza (Group)

To subscribe to our free, monthly mass spectrometry newsletter, please send an e-mail to and simply fill the subject line with the word »MSC Newsletter«

Find more infos about advertising at [iito] web portals in our media flyer [iito] in a Nutshell [PDF file]

Please visit also our web portals for the Eurpean life sciences and the life sciences in German-speaking Europe (DE, AT & CH) at and


Picture Stier Group MIXiii Lifescience Healthtech Conference 650x300px

» top