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Affymetrix, Inc.. (5/8/14). "Press Release: Affymetrix and Leica Biosystems Announce the Launch of Fully Automated RNA in situ Hybridization Assays". Santa Clara, CA.

Organisations Organisation Affymetrix Inc. (Nasdaq: AFFX)
  Group Thermo Fisher (Group)
  Organisation 2 Leica Biosystems (biosystems division of Leica Microsystems)
  Group Danaher (Group)
Products Product ViewRNA™ eZ assay (automated RNA in situ hybridisation assay)
  Product 2 Leica BOND RX staining system
Index term Index term Affymetrix–Danaher: lab automation, –201405 collab product integration fully automated ViewRNA eZ Assays on Leica BOND RX staining platform
Persons Person Last, Andrew J. (Andy) (Bio-Rad 201904– COO before Berkeley Lights + Intrexon + Affymetrix + BD Biosciences)
  Person 2 Litow, Micah (Danaher 201405 Director Reserarch + Innovation Advanced Staining Instruments at Leica Biosystems)

ViewRNATM eZ Assays, fully automated on the Leica BOND RX, offer remarkable sensitivity and specificity of staining for coding and non-coding markers in an easy-to-use, fully automated format.

Affymetrix, Inc. (NASDAQ:AFFX) and Leica Biosystems announce the launch of Affymetrix' fully automated RNA in situ hybridization assays ViewRNATM eZ Assays on the Leica BOND RX staining platform. These assays detect coding RNA as well as novel non-coding markers in formalin-fixed paraffin-embedded (FFPE) tissues. Dedicated for research use only*, the assays provide researchers with a powerful automated solution for drug discovery, translational research, and the development of new diagnostic tests for personalized medicine. The automation significantly reduces hands-on time and assay run time for profiling single-cell gene expression.

The Leica BOND RX system automates the staining process, bringing all the benefits of consistency, reduced labor, and speed. This fully automated assay is hands-free from tissue de-waxing to counter staining, and offers high sensitivity, specificity, and reproducibility with easy standardization across laboratories. ViewRNA eZ Assays represent a major technological advancement offering a robust and reliable platform to easily interrogate the function and disease relevance of any expressed genes.

"In particular, the ability to target non-coding as well as coding transcripts opens up a significant new capability to discover powerful new biomarkers for molecular test development, as the importance of the non-coding regions of the transcriptome are becoming more and more evident," said Andrew Last, PhD, Chief Operating Officer at Affymetrix. "In addition, researchers can now design probes to visualize RNA transcripts coding for secreted proteins, which are important targets that traditional immunohistochemistry assays have challenge detecting."

Micah Litow, Director, Research & Innovation, Advanced Staining Instruments at Leica Biosystems added: "Leica is very excited that the BOND RX is fully automating the Affymetrix ViewRNA eZ Assays. We are proud to have put such a powerful tool into the hands of the dedicated researchers who are making important discoveries, increasing our knowledge and improving cancer diagnostics."

Affymetrix' ViewRNA eZ Assays on the Leica BOND RX platform are now available for research applications. The ViewRNA eZ staining protocol is pre-loaded onto the Leica BOND RX, and the staining kit optimized for FFPE samples and probes of choice are available from Affymetrix.

*For Research Use Only. Not for use in diagnostic procedures.

PLEASE NOTE: Affymetrix, the Affymetrix logo, and ViewRNA are trademarks of Affymetrix, Inc. All other trademarks and product names are the property of their respective owners.

About Leica Biosystems

Leica Biosystems is a global leader in workflow solutions and automation, striving to advance cancer diagnostics to improve patients' lives. Leica Biosystems provides anatomical pathology laboratories and researchers a comprehensive product range for each step in the pathology process, from sample preparation and staining to imaging and reporting. Leica's easy-to-use and consistently reliable offerings help improve workflow efficiency and diagnostic confidence. The company is represented in over 100 countries and is headquartered in Nussloch, Germany.

About Affymetrix

Affymetrix technologies enable multiplex and simultaneous analysis of biological systems at the cell, protein, and gene level, facilitating the rapid translation of bench-top research into clinical and routine use for human health and wellness.

The Company provides leadership and support, partnering with customers in pharmaceutical, diagnostic, and biotechnology companies, as well as leading academic, government, and non-profit research institutes in their quest to use biology for a better world.

More than 2,300 microarray systems have been shipped around the world and more than 65,000 peer-reviewed papers have been published citing Affymetrix technologies. Affymetrix is headquartered in Santa Clara, California, and has manufacturing facilities in Cleveland, Ohio, San Diego, Vienna, and Singapore. The Company has about 1,100 employees worldwide and maintains sales and distribution operations across Europe, Asia, and Latin America. For more information about Affymetrix, please visit

Forward-looking statements

All statements in this press release that are not historical are "forward-looking statements" within the meaning of Section 21E of the Securities Exchange Act as amended, including statements regarding Affymetrix' "expectations," "beliefs," "hopes," "intentions," "strategies," or the like. Such statements are subject to risks and uncertainties that could cause actual results to differ materially for Affymetrix from those projected. These and other risk factors are discussed in Affymetrix' Form 10-K for the year ended December 31, 2013, and other SEC reports for subsequent quarterly periods.

Affymetrix, Inc.

Mindy Lee-Olsen, 408-731-5523
Vice President, Marketing Services


Doug Farrell, 408-731-5285
Vice President, Investor Relations


Leica Biosystems
Tim Lyons, +61 (0) 400 990 975
Global Marketing Communications Director

Record changed: 2016-03-20


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