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AB Sciex (d/b/a Sciex). (2/26/18). "Press Release: Sciex Launches OptiFlow Quant Solution for BioPharma Peptide Quantitation". Framingham, MA.

Organisations Organisation AB Sciex (Danaher, Framingham, MA)
  Group Danaher (Group)
  Organisation 2 Notch Communications Ltd.
  Group Notch Communications (Group)
Products Product OptiFlow Quant Solution for BioPharma Peptide Quantitation
  Product 2 M5 Microflow LC
Persons Person Gostick, Dominic (Dom) (Danaher 201802 VP + General Manager LC/MS Business joined 200401 before Waters)
  Person 2 Whelan, Kate (Notch Communications 201108 COO)

Solution offers researchers increased sensitivity without sacrificing robustness or usability

SCIEX, a global leader in life science analytical technologies, today introduced the OptiFlow Quant Solution for easy yet highly sensitive biomolecule quantitation. This latest addition to the growing line of SCIEX solutions for biopharmaceutical laboratories comprises the new M5 Microflow LC with Phenomenex microflow columns and new OptiFlow™ Turbo V™ Source. It offers scientists the most flexible microflow quantitation solution with better sensitivity than analytical flow systems, but without sacrificing robustness or usability. Pharmaceutical, biopharmaceutical and contract research organizations (CRO) currently struggling with bioanalysis projects on challenging analytes, such as peptides, mAbs, and ADCs, will now be able to obtain better data while achieving maximal throughput by utilizing microflow separations, without the traditional complex setup and impact of low flow workflows.

Development of novel therapeutics and biotherapeutics creates a challenge for scientists to accurately detect and quantify these compounds. Researchers are tasked with developing quantitation methods that are both sensitive and selective enough to be used in bioanlaytical studies to support drug development. The OptiFlow Quant Solution from SCIEX brings the powerful sensitivity boost from microflow LC without sacrificing the ease-of-use and robustness of analytical flow assays. Scientists are able to gain sensitivity of analyte detection with an easy to implement setup,that still provides maximal flexibility to ensure it can handle novel therapeutics coming through the pipeline in the future.

The SCIEX new OptiFlow Quant Solution comprises:

> M5 Microflow LC - The new microflow LC now has flow rate capabilities from 1-200 µL/min flow ranges, along with an auto-sealing injection needle, updated auto sampler with injector wash pumps and vial bottom sensing technology. Standard size, finger-tight fittings make the setup and use of the M5 Microflow LC simple and tool-free.

> Phenomenex MicroFlow Columns - SCIEX has partnered with Phenomenex, which has a wide portfolio of microflow columns across a large number of column chemistries, to give flexible column choice for all project needs.

> OptiFlow Turbo V Source - The new single-click source is based on the market leading Turbo V Source technology and requires no physical adjustments for optimal ionization performance. The OptiFlow Turbo V Source supports a wide flow rate range, and includes a column heater that goes up to 90°C for challenging analyte separations, and utilizes standard size finger-tight fittings for a tool-free setup.

> 6500+ Triple Quad or QTRAP® MS Systems - Paired with an industry leading SCIEX mass spectrometer, the OptiFlow Quant Solution offers proven sensitivity and robustness with compliant software processing for even the more regulated environments. These high performance MS systems empower users with the highest quality data and uptime for the entire study.

"With our innovations in microflow chromatography and MS source technology, SCIEX users now have a simple and easy path to boost sensitivity, allowing the laboratory to reach the ultimate limits of quantitation," said Dominic Gostick, Vice President and General Manager, LC/MS Business at SCIEX. "The OptiFlow Quant Solution enables researchers to easily adopt microflow workflows that save time and cost, and improve throughput for development of quantitation methods for challenging analytes."

Learn more about the new OptiFlow Quant Solution


SCIEX helps to improve the world we live in by enabling scientists and laboratory analysts to find answers to the complex analytical challenges they face. The company's global leadership and world-class service and support in capillary electrophoresis and liquid chromatography-mass spectrometry have made it a trusted partner to the thousands of scientists and lab analysts worldwide who are focused on basic research, drug discovery and development, food and environmental testing, forensics and clinical research.

With over 40 years of proven innovation, SCIEX excels by listening to and understanding the ever-evolving needs of its customers to develop reliable, sensitive and intuitive solutions that continue to redefine what is achievable in routine and complex analysis. For more information, please visit

SCIEX social: Twitter, LinkedIn, and on Facebook.

For research use only. Not for use in diagnostic procedures. RUO-MKT-12-7226-A

AB Sciex is operating as SCIEX.
© 2018 AB Sciex. The trademarks mentioned herein are the property of the AB Sciex Pte. Ltd. or their respective owners. AB Sciex™ is being used under license.

Contact Information

Victoria Parr
Global Marketing Director, SCIEX Editorial follow-up

Kate Whelan
Notch Communications
+44 161 457 7230 / +46 702 38 11 49


Record changed: 2023-06-05


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