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Shimadzu Corporation. (10/4/10). "Press Release: GC/MS Forensic Toxicological Database Provides Easy Analysis of Toxicological Substances in the Field of Forensic Medicine".

Organisation Organisation Shimadzu Corporation
  Group Shimadzu (Group)
Products Product GC/MS Forensic Toxicological Database (Shimadzu)
  Product 2 GCMS-QP2010 Ultra mass spectrometer
     


Shimadzu's GC/MS Forensic Toxicological Database enables quick and easy identification of 1,011 types of illegal drugs and pharmaceuticals using a gas chromatograph - mass spectrometer (GC/MS). It is intended for toxicological analyses by law enforcement agencies and for use in university settings.

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* A gas chromatograph - mass spectrometer (GC/MS) connects a mass spectrometer (MS) to a gas chromatograph (GC). Samples containing a mix of components are vaporized at high temperatures, and each component is separated in a column with an inner diameter of 0.2 to 0.5 mm (GC unit). The separated components are then ionized, yielding mass spectra that enable reliable qualitative and quantitative analysis of each component.
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Background to the Product Release

There has been a never-ending stream of cases involving the use of toxicological substances. These cases typically involve the abuse of drugs and stimulants, and poisonings by pharmaceuticals or agricultural chemicals. In recent years, this has become a significant social problem. One method of quickly identifying such toxicological substances is to analyze them using a gas chromatograph - mass spectrometer, and then compare the results with existing standard samples. However, acquiring standard samples is difficult, and multiple instrument operating methods are problematic. A GC/MS system capable of easy component identification without standard samples would greatly simplify identification. Using the GC/MS Forensic Toxicological Database provides easy, high-speed, highly accurate analysis of toxicological substances.

Features of This Product

1. Capable of batch analysis of database registered components in 40 minutes

Analysis via a gas chromatograph - mass spectrometer, utilizing the Scan method for the comprehensive detection of components, has conventionally been used for the analysis of unknown samples when making forensic medical determinations. The Scan method enables comprehensive detection of target components, without the need of narrowing down to specific substances. Moreover, mass spectra, which are effective for identifying components in unknown samples, can be obtained. The combination of this database with the Shimadzu GCMS-QP2010 Ultra, which boasts highly sensitive scanning performance, enables batch detection of multiple components and the identification of toxicological substances.

2. Registration of 1,011 forensic toxicological components

This database contains mass spectra and retention indices for 1,011 types of forensic toxicological substances (including derivatives*), such as illegal drugs, psychotropics, sedatives and other pharmaceuticals, and agricultural chemicals. In addition, regarding illegal drugs, 208 components, which have been documented in recent years, are registered, enabling component confirmation despite difficulties with the acquisition of standard samples.

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* Some compounds have structures that are not suited to analysis. Derivatization refers to the changing of properties in such cases by replacing a portion of the structure with a structure suited to analysis.
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3. Analysis preparations consist simply of downloading analysis methods

The database contains the GCMS-QP2010 Ultra analysis methods. Measurement preparations can be performed simply by downloading the method to the system. The method contains retention indices, and components are identified from accurately calculated retention times.

4. Mass spectral library provides even more reliable component identification

The database contains a mass spectral library of 1,011 types of forensic toxicological substances. Since retention indices are registered in the library, reliable confirmations can be performed through similarity searches in combination with retention indices, even for the many forensic toxicological substances with similar mass spectra.

This database was developed specifically for forensic toxicological substances utilized in poisonings, drug abuse, and other illegal behavior. The database makes it possible for the police and forensic medical classrooms to create an easy, reliable GC/MS inspection system for the investigation of 1,011 types of forensic toxicological components. This product is intended to contribute to the promotion of investigations in the context of scientific crime detection and forensic medical determinations. In addition, the goal is to expand our market share of gas chromatograph - mass spectrometers in the forensic medical market, both in Japan and overseas.

[ More information at product page at http://www.shimadzu.com/products/lab/ms/5iqj1d000000lw44.html ]

   
Record changed: 2019-06-09

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