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Thermo Fisher Scientific Inc.. (5/16/18). "Press Release: Thermo Fisher Scientific Installs First Glacios Cryo-Electron Microscope for Drug Discovery and Development". Hillsboro, OR.

	Region	Cambridge, Cambridgeshire
	Country	United Kingdom (GB)
	Organisation	Thermo Fisher Scientific Inc., Hillsboro, OR (formerly FEI Company)
	Group	Thermo Fisher (Group)
	Organisation 2	Astex Pharmaceuticals Ltd.
	Group	Otsuka (Group)
	Product	Glacios Cryo Transmission Electron Microscope (Cryo-TEM)
	Product 2	drug discovery
	Index term	Otsuka–Thermo Fisher: electron microscope, 201805 supply of Glacios Cryo-TEM to Astex Pharmaceuticals Ltd
	Index term 2	Univ Cambridge–Thermo Fisher: electron microscope, 201805 supply existent Krios Cryo-TEM at Cambridge Univ
	Person	Jhoti, Harren (Otsuka 201805 CEO of Astex Pharmaceuticals)
	Person 2	Shafer, Michael (Mike) (Thermo Fisher 201602 President Chemical Analysis)

Breakthrough platform optimizes productivity and expands cryo-EM entry path for a broader range of researchers

Thermo Fisher Scientific, the world leader in serving science, today announced Astex Pharmaceuticals, a leader in innovative drug discovery and development, selected the Thermo Scientific Glacios Cryo Transmission Electron Microscope (Cryo-TEM) to aid in its drug discovery and development program. Astex's research focuses on oncology and diseases of the central nervous system. They will install the Glacios Cryo-TEM at their research and development headquarters in Cambridge, UK.

Astex is one of five pharmaceutical companies participating with Thermo Fisher in the Cambridge Pharmaceutical Cryo-EM Consortium. Designed-in connectivity between the Glacios Cryo-TEM and the high-performance Thermo Scientific Krios Cryo-TEM system, located at nearby Cambridge University, will allow researchers to optimize their productivity. Scientists will be able to first prescreen samples on the Glacios Cryo-TEM to find the best quality samples before advancing to the higher resolution imaging on the Krios Cryo-TEM.

Dr. Harren Jhoti, president and chief executive officer of Astex, said, "We are excited to be the first company in the world to have a new Glacios system installed in-house. We believe it will make an important contribution as we explore the potential of cryo-EM in our search for important new therapeutic agents."

"The acceptance and adoption of Thermo Scientific cryo-EMs within the pharmaceutical industry has accelerated over the last year, and we are pleased the Glacios will be part of the vital research Astex is undertaking," said Mike Shafer, president, materials and structural analysis, Thermo Fisher. "The Glacios is a critical step in accelerating the workflow process for scientists researching pharmaceutical solutions for treating diseases."

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of more than $20 billion and approximately 70,000 employees globally. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics, deliver medicines to market and increase laboratory productivity. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive services. For more information, please visit www.thermofisher.com.

Media Contact Information:

Kathy Gill
Thermo Fisher Scientific
+1 503-726-7684
kathy.gill@thermofisher.com

Sandy Fewkes
MindWrite Communications
+1 408-224-4024
sandy@mind-write.com

Record changed: 2023-06-05