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Alzheimer’s Disease Metabolomics Consortium’s (ADMC)

The Alzheimer Disease Metabolomics Consortium (ADMC), led by Prof. Rima Kaddurah-Daouk at Duke University, is a bold initiative that brings together leaders in Alzheimer’s disease (AD) clinical and basic research to work in close collaboration with centres of excellence in metabolomics, genetics, biochemistry, engineering, and bioinformatics. We aim to define metabolic failures across the trajectory of disease connecting peripheral and central changes. We define alterations in biochemical pathways and networks that can help us gain deeper understanding of disease mechanisms and that can highlight novel targets for drug design. We are a part of the National Institute on Aging’s (NIA) funded national initiatives that includes Accelerated Medicine Partnership for Alzheimer Disease (AMP-AD) and Molecular Mechanisms of Vascular Etiology of Alzheimer Disease (M2OVE-AD). Connecting metabolomics data to genomics, imaging and other rich omics data in a systems biochemical approach we seek to sub-stratify AD stepping towards a precision medicine approach for disease classification and management. The end results of metabolic profiling of large AD cohorts and community studies is leading the way to the creation of a national database for AD and an Atlas that can enable the AD community with a road map for novel drug discovery. All data generated by the consortium is made publicly available. We are partners with other consortia embedded within AMP-AD and M2OVE-AD where different types of large data are being used to inform one another creating an unparalleled opportunity to generate new hypothesis about disease mechanisms. *

 

Period Start 2018-07-25 existent
Product Industry metabolomics
     
  City n. a. 
    Address record changed: 2018-08-15
     
Basic data Employees n. a.
     
    * Document for �About Section�: Biocrates Life Sciences AG. (7/25/18). "Press Release: AAIC Researchers Report New Data on How Gut Bacteria and Lipid Metabolism May Influence Alzheimer’s and Other Brain Diseases". Innsbruck.
     
   
Record changed: 2018-08-15

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More documents for Alzheimer’s Disease Metabolomics Consortium’s (ADMC)


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